Differential Diagnosis: Hypoglycemia

Following are differential diagnoses, listed in order of likeliness, for patients presented with hypoglycemia.

• Spurious (eg, storage artifact)

• Neonates (typically <6 weeks of age; normal finding or related to another condition [eg, portosystemic shunt])

• Toy-breed puppy (can occur in healthy puppies when fasting or if no access to nursing)

• Exogenous insulin overdose

• Hepatic failure

• Portosystemic shunt

• Hypoadrenocorticism

• Sepsis

• Systemic inflammatory response syndrome

• Insulinoma

• Xylitol toxicity

• Paraneoplastic syndrome (eg, leiomyoma/leiomyosarcoma, hepatoma)

• High-intensity exercise

• Pituitary dwarfism

• Glycogen storage disease

• Renal glucosuria

• Polycythemia

• Oleander toxicity

• Amphetamine-dextroamphetamine toxicity

• Trypanosoma congolense infection (only in specific geographic regions)